News
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April 30, 2008
The DiRE tool operates with new ECR Browser alignments now. It is also possible to run DiRE on human (hg18), mouse (mm9), and rat (rn4) genomes.
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Whole genome alignments
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ECR Browser -- Evolutionary conservation of multiple genomes. Identification and sequence analysis of regulatory elements. Genome Alignment in ECR Browser -- Align your FASTA nucleotide sequence to a genome of choice.
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Multiple and pairwise sequence alignments
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Mulan -- Full multiple sequence alignment. [Interactive conservation profiles, phylogenetic trees, etc.]
zPicture -- Stacked pairwise and multiple sequence alignment.
eShadow -- Phylogenetic shadowing of closely related species.
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Regulation of co-expressed genes
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DiRE -- Identification of proximal and Distant Regulatory Elements of co-regulated genes. SynoR -- Prediction of synonymous regulatory elements in vertebrate genomes.
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Identification of conserved transcription factor binding sites (cTFBS)
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Excluding up to 95% false positive TFBS predictions using sequence conservation as a filter.
multiTF -- cTFBS in multiple sequence alignments.
rVista 2.0 -- cTFBS in pairwise alignments.
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Additional resources
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