Journal Club Archive

Page wizard: Sanjar

Presentation DatePresenterManuscript
6/2023SanjarRozowsky et al. "The EN-TEx resource of multi-tissue personal epigenomes & variant-impact models". Cell 2023
5/2023SanjarXue et al. "The functional and evolutionary impacts of human-specific deletions in conserved elements". Science 2022
5/2023MehariNarita et al. Acetylation of histone H2B marks active enhancers and predicts CBP/p300 target genes. Nature Genetics 2023
4/2023SanjarConnally et al. "The missing link between genetic association and regulatory function". eLife 2022
4/2023WeiJoung et al. "A transcription factor atlas of directed differentiation". Cell 2023
3/2023DiHansen et al. "ATAC-STARR-seq reveals transcription factor–bound activators and silencers within chromatin-accessible regions of the human genome". Genome Research 2022
3/2023SanjarWang et al. "HiDRA: High-resolution genome-wide functional dissection of transcriptional regulatory regions and nucleotides in human". Nature Communications 2018
2/2023SanjarDavis et al. "The Relationship Between Precision-Recall and ROC Curves". ICML 2006
1/2023JayaBorsari et al. "Enhancers with tissue-specific activity are enriched in intronic regions". Genome Research 2021
1/2023MehariOliva et al. "DNA methylation QTL mapping across diverse human tissues provides molecular links between genetic variation and complex traits". Nature Genetics 2022
1/2023SanjarDonohue et al. "A cis-regulatory lexicon of DNA motif combinations mediating cell-type-specific gene regulation". Cell Genomics 2022
11/2022WeiHerring et al. "Human prefrontal cortex gene regulatory dynamics from gestation to adulthood at single-cell resolution". Cell 2022
10/2022WeiWatanebe et al. "A global overview of pleiotropy and genetic architecture in complex traits". Nature 2019
7/2022SanjarChet et al. "A sequence-based global map of regulatory activity for deciphering human genetics". Nature Genetics 2022
7/2022MehariHuang et al. "Densely Connected Convolutional Networks". IEEE 2017
7/2022MehariWolfe et al. "An explainable artificial intelligence approach for decoding the enhancer histone modifications code and identification of novel enhancers in Drosophila". Genome Biology 2021
7/2022JayaCarullo et al. "Enhancer RNAs predict enhancer-gene regulatory links and are critical for enhancer function in neuronal systems". NAR 2020
6/2022SanjarNeumayr et al. "Differential cofactor dependencies define distinct types of human enhancers". Nature 2022
5/2022SanjarSahu et al. "Sequence determinants of human gene regulatory elements". Nature Genetics 2022
2/2021-Uebbing et al. "Massively parallel discovery of human-specific substitutions that alter enhancer activity". PNAS 2020
1/2021-Kvon et al. "Enhancer redundancy in development and disease". Nature Review Genetics 2021
Half a decade later...
Presentation DateManuscript
1/12/16J.L. Payne and A. Wagner, Mechanisms of mutational robustness in transcriptional regulation, Front Genet. 2015; 6: 322.
2/2/16Oldridge et al., Genetic predisposition to neuroblastoma mediated by a LMO1 super-enhancer polymorphism, Nature 2015; 528, 418 21
2/16/16Ioniata-Laza et al., A spectral approach integrating functional genomic annotations for coding and noncoding variants, Nat Genet. 2016 Feb;48(2):214-20
4/5/16Villar, Diego, et al., Enhancer evolution across 20 mammalian species, Cell 160.3 (2015): 554-566
4/12/16Raluca Gordan, et al., How do closely related transcription factors target distinct genomic regions, Conference talk: Systems Biology 2016
4/12/16Robin D Dowell, et al., RNA Pol II modeling predicts active transcription factors, Conference talk: Systems Biology 2016
4/12/16Joanna Wysocka, et al., Cellular anthropology can be used to identify cis-regulatory divergence in the human and chimp neural crest?, Conference talk: Systems Biology 2016
4/12/16Charles G Danko, et al., Widespread stabilizing and positive selection govern primate enhancer evolution, Conference talk: Systems Biology 2016
4/19/16A. K. Holloway et al., Accelerated evolution of enhancer hotspots in the mammal ancestor, Molecular biology and evolution (2015): msv344