Group Meetings
Wednesdays at 10:00am, the 6th floor conference room
| Presentation date | Presenter | Progress Report | Journal Club | |
|---|---|---|---|---|
| 2026 | ||||
| 7/2 | Jaya | "Tahoe-100M: A Giga-Scale Single-Cell Perturbation Atlas for Context-Dependent Gene Function and Cellular Modeling" (https://www.biorxiv.org/content/10.1101/2025.02.20.639398v3) | ||
| 7/15 | Yash, Shivang, and Vayun | progress reports | ||
| 7/22 | Gaetano | "Non-coding genetic variants underlying higher prostate cancer risk in men of African ancestry" (https://www.nature.com/articles/s41467-025-64631-4) | ||
| 7/29 | Yash, Shivang, and Vayun | poster presentations | ||
| 9/9 | Lab | Claude Science | ||
| 9/23 | Xandra | An expanded codebook of human transcription factor DNA-binding specificity | ||
| 10/07 | Ivan | "Editing GWAS: experimental approaches to dissect and exploit disease-associated genetic variation" (https://link.springer.com/article/10.1186/s13073-021-00857-3) | ||
| 10/21 | Stas | "Decoding common and rare noncoding variant effects across cellular and developmental contexts" (https://www.nature.com/articles/s41588-026-02619-6) | ||
| 11/04 | Jaya | TBD |
Papers to present:
"Intrinsic promoter responsiveness dictates sensitivity to transcriptional activation by enhancers"
(https://www.biorxiv.org/content/10.64898/2026.06.25.734173v1)
"Decoding common and rare noncoding variant effects across cellular and developmental contexts"
(https://www.nature.com/articles/s41588-026-02619-6)
"Gene regulatory landscape dissected by single-cell four-omics sequencing"
(https://www.nature.com/articles/s41586-026-10322-z)
"Linking GWAS risk genes to transcriptional features of major depressive disorder via in vivo Perturb-seq"
(https://www.nature.com/articles/s41588-026-02638-3)
"Non-coding genetic variants underlying higher prostate cancer risk in men of African ancestry" (https://www.nature.com/articles/s41467-025-64631-4)
"A plasma proteomics-based candidate biomarker panel predictive of amyotrophic lateral sclerosis" (https://www.nature.com/articles/s41591-025-03890-6)
Borzoi (https://www.biorxiv.org/content/10.1101/2023.08.30.555582v1.full.pdf)
Evaluation of deep learning approaches for high-resolution chromatin accessibility prediction from genomic sequence
https://www.biorxiv.org/content/10.1101/2025.03.01.641000v1.abstract
Deep learning-based models for preimplantation mouse and human embryos based on single-cell RNA sequencing
https://www.nature.com/articles/s41592-024-02511-3#Sec19
"Functional dissection of complex trait variants at single-nucleotide resolution"
https://www.nature.com/articles/s41586-026-10121-6
"Editing GWAS: experimental approaches to dissect and exploit disease-associated genetic variation"
https://link.springer.com/article/10.1186/s13073-021-00857-3
"Gigabase-scale deletion scanning of the human genome"
https://www.biorxiv.org/content/10.64898/2026.05.29.728882v1.full
"An expanded codebook of human transcription factor DNA-binding specificity"
https://www.nature.com/articles/s41586-026-10798-9
https://www.nature.com/articles/s41588-026-02670-3
Project discussions (Monday meetings)
- Monday, 9:30 am - Stas
- Monday, 10:00 am - Di
- Monday, 10:30 am - Alexandra
- Monday, 11:00 am - Jaya
Acknowledgement (included in publications)
This research was supported [in part] by the Intramural Research Program of the National Institutes of Health (NIH). The contributions of the NIH author(s) are considered Works of the United States Government. The findings and conclusions presented in this paper are those of the author(s) and do not necessarily reflect the views of the NIH or the U.S. Department of Health and Human Services.
Group Members